Antibiotics - The Perfect Storm

We need new antibiotics to fight infections caused by resistant bacteria. But the marketplace, the structure of the pharmaceutical industry, regulatory agencies, and difficult science are conspiring to deny us the products we need. This blog will present perspectives and developments in the fight for new antibiotics.

Sunday, March 19, 2023

I am moving my blog

You can find archived articles and new blogs on davidshlaes.substack.com. Blogger has just become too restrictive. I apologize for any inc...

Tuesday, March 14, 2023

Antibiotic Biotech Execs Share Their Concerns

Since the vast majority of products in the antibiotic pipeline, from early discovery through late-stage clinical development, comes from b...

Monday, January 16, 2023

The Fate of Another Antibiotic Biotech - Nabriva

Last week, a small, publicly held antibiotic biotech, Nabriva, announced that they would wind down their operations. Everyone still there ...

Friday, December 23, 2022

The Grinch Stole PASTEUR

Antibiotic resistant infections are rising. Deaths from these infections are rising. The US is no exception. The dwindling antibio...

Monday, October 10, 2022

PASTEUR, Do or . . .

A recent article in Politico (blogger won’t let me use links for some reason), suggests that there is a good chance PASTEUR won’t pass thi...

Monday, August 22, 2022

Why Antibiotics Don't Work - Implications for Clinical Trial Design

I want to discuss the idea of superiority trials for antibiotics and some of the issues that many experienced researchers fail to consider...

Tuesday, April 12, 2022

ASM Microbe - Antimicrobial Agents and Resistance

Guest Blogger Krisztina M. Papp-Wallace Introducing the ASM Microbe 2022 Antimicrobial Agents and Resistance Program Dear AAR community...

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