Antibiotics - The Perfect Storm

We need new antibiotics to fight infections caused by resistant bacteria. But the marketplace, the structure of the pharmaceutical industry, regulatory agencies, and difficult science are conspiring to deny us the products we need. This blog will present perspectives and developments in the fight for new antibiotics.

Friday, December 23, 2022

The Grinch Stole PASTEUR

Antibiotic resistant infections are rising. Deaths from these infections are rising. The US is no exception. The dwindling antibio...

Monday, October 10, 2022

PASTEUR, Do or . . .

A recent article in Politico (blogger won’t let me use links for some reason), suggests that there is a good chance PASTEUR won’t pass thi...

Monday, August 22, 2022

Why Antibiotics Don't Work - Implications for Clinical Trial Design

I want to discuss the idea of superiority trials for antibiotics and some of the issues that many experienced researchers fail to consider...

Tuesday, April 12, 2022

ASM Microbe - Antimicrobial Agents and Resistance

Guest Blogger Krisztina M. Papp-Wallace Introducing the ASM Microbe 2022 Antimicrobial Agents and Resistance Program Dear AAR community...

Monday, March 28, 2022

Pull Incentives for Antibiotic R&D and Private Investment

John Rex (thank you) just sent out an email highlighting a paper emanating from the Milliken Institute on how private investment could...

Monday, February 14, 2022

The Future of Antibiotics

Spoiler alert – get out the anti-depressants. Before I get to the issue at hand, I need to share with you my recent experience posting bl...

Monday, February 7, 2022

Entasis, Antibiotics and the Dodo

And again! Entasis Therapeutics has been struggling in the public marketplace. There is certainly a risk that it will be going the way of...

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