Antibiotics - The Perfect Storm

We need new antibiotics to fight infections caused by resistant bacteria. But the marketplace, the structure of the pharmaceutical industry, regulatory agencies, and difficult science are conspiring to deny us the products we need. This blog will present perspectives and developments in the fight for new antibiotics.

Monday, April 15, 2019

Pull Incentives - Don't Hold Your Breath!

Months ago, long before the 2018 election, I was led to believe that Senate candidate Jackie Rosen of Nevada was seriously interested i...

Friday, March 29, 2019

Non-Traditional Antibacterials

We had our webinar - Clinical development for non-developers Part 3: Non-traditional Approaches yesterday. I encourage everyone int...

Tuesday, March 12, 2019

Regulatory Conundrums

In the absence of any real news on the pull incentive front, I want to turn my attention to the regulatory side of antibiotic developm...

Monday, February 11, 2019

Antibiotics - Play or Pay?

In my last blog I discussed the potential pull incentive proposed in the UK Plan to tackle antimicrobial resistance. One of the other ...

Thursday, January 31, 2019

The UK Plan

The United Kingdom recently released a 5-year and a 20-year plan for combatting antimicrobial resistance. These are both worth a ca...

Tuesday, January 22, 2019

Musings on Penicillin - Can we Learn From History?

Lately, I’ve been thinking about new approaches to antibacterial therapy. But I keep going back to some old family history. It was 1944. ...

Wednesday, December 26, 2018

Antibiotics in 2019?

Antibiotic R&D has had a particularly bad year starting with The Medicines Company who abandoned their antibiotic R&D effort...

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