Antibiotics - The Perfect Storm

We need new antibiotics to fight infections caused by resistant bacteria. But the marketplace, the structure of the pharmaceutical industry, regulatory agencies, and difficult science are conspiring to deny us the products we need. This blog will present perspectives and developments in the fight for new antibiotics.

Monday, February 29, 2016

What if . . . ?

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First, I need to apologize to my readers.   I took almost the entire month of February off to escape the New England winter – hence the lag...
Tuesday, January 26, 2016

Big Pharma and Antibiotic R&D - An Update

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Today I went back to the book I wrote back in 2010 – Antibiotics – The Perfect Storm.   In that book I had a table showing the number of ...
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Wednesday, January 13, 2016

AstraZeneca Where Are You?

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You will all remember that mcr-1 mediated resistance to polymyxin (colistin) emerged on transmissible plasmids last year.   How did it a...
Sunday, January 3, 2016

2015 - Year in Review

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The highlights of the year 2015 for me begin with the discovery of the iChip technology by Stava Epstein and his colleagues in Kim Lewis...
Saturday, December 19, 2015

Infection Control in a Small Hospital

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Today I want to continue talking about what its like to work in infection control in a small hospital.   About 70% of all hospitals in the ...
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