Antibiotics - The Perfect Storm

We need new antibiotics to fight infections caused by resistant bacteria. But the marketplace, the structure of the pharmaceutical industry, regulatory agencies, and difficult science are conspiring to deny us the products we need. This blog will present perspectives and developments in the fight for new antibiotics.

Thursday, January 21, 2010

Consolidation, de-consolidation and antibiotics.

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Over the last 30 years there has been tremendous consolidation within the pharmaceutical industry. In 2003, Karen Bush of Johnson and Johns...
Thursday, January 14, 2010

Connecting the dots . . . not.

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For this blog, I was inspired by the events following the failed underwear bombing of a US bound airliner on Christmas day and research I di...
Saturday, January 9, 2010

And then there was none.

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I was contacted recently by a journalist about antibiotics in development for Gram negative infections. The subject of carbapenem resistanc...
Thursday, December 31, 2009

Hope and skepticism for 2010.

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I have been reviewing recent efforts in Europe to deal with the antibiotic conundrum. I am astonished that Europe is so far ahead of the US...
Thursday, December 24, 2009

A Bittersweet End to 2009

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Here it is, Christmas eve, and I'm blogging about antibiotics. What is wrong with me? The end of this year is bittersweet for me. I h...
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Friday, December 11, 2009

The FDA, pneumonia and new antibiotics - Progress?

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The FDA met with its Anti-infectives Drug Advisory Committee on Dec. 9 to discuss how industry should design clinical trials for new antibio...
Friday, November 20, 2009

The FDA - another blow to antibiotics?

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More and more pharmaceutical companies are abandoning the field of antibiotics research. The markets are marginal compared to treatment of ...
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